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Invitrogen™ KIR2DL4 Polyclonal Antibody
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Catalog No. PIPA5115470
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100 μL
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PIPA5115470 100 μL
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Catalog No. PIPA5115470 Supplier Invitrogen™ Supplier No. PA5115470
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KIR2DL4.

CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIR2DL4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KIR2DL4
Gene Accession No. Q99706
Gene Alias CD158 antigen-like family member D; CD158D; G9P; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4; killer cell immunoglobulin-like receptor 2DL4; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4; killer cell inhibitory receptor 103AS; killer Ig receptor; killer-cell immunoglobulin-like receptor; killer-cell immunoglobulin-like receptor 2DL4; KIR; KIR103; KIR103AS; KIR-103AS; KIR2DL4; KIR-2DL4; MHC class I NK cell receptor KIR103AS; natural killer cell inhibitory receptor; natural killer cell receptor; NK cell receptor
Gene Symbols KIR2DL4
Host Species Rabbit
Immunogen A synthesized peptide derived from human KIR2DL4(Accession Q99706), corresponding to amino acid residues F78-L128.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3805
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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