Invitrogen™ Kir3.1 (KCNJ3) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597258

Catalog No. PIPA597258

Description

Immunogen sequence: NGRCNVQHGN LGSETSRYLS DLFTTLVDLK WRWNLFIFIL TYTVAWLFMA SMWWVIAYTR GDLNKAHVGN YTPCVANVYN FPSAFLFFIE TEATIGYGYR Y; Positive Samples: Mouse brain, Rat brain; Cellular Location: Membrane, Multi-pass membrane protein.

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Specifications

• Antigen: Kir3.1 (KCNJ3)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ3
• Gene Alias: EGK_04447; G protein-activated inward rectifier potassium channel 1; GIRK1; GIRK-1; HGIRK1; inward rectifier K(+) channel Kir3.1; inward rectifier K+ channel KIR3.1; Kcnf3; Kcnj3; KGA; KGB1; KIR3.1; potassium channel inwarding rectifying channel subfamily J member 3; potassium channel subunit Kir3.1 type 3 delta; potassium channel, inwardly rectifying subfamily J member 3; potassium channel, inwardly rectifying subfamily J, member 3; potassium inwardly rectifying channel subfamily J member 3; potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e; potassium inwardly-rectifying channel, subfamily J, member 3; potassium voltage-gated channel subfamily J member 3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16519, 3760, 50599
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.912 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P48549, P63250, P63251
• Gene Symbols: KCNJ3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ3 (NP_0022301).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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