Invitrogen™ Kir3.1 (KCNJ3) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599646

Catalog No. PIPA599646

Description

Antibody detects endogenous levels of total GIRK1/KIR3.1/KCNJ3.

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Specifications

• Antigen: Kir3.1 (KCNJ3)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ3
• Gene Alias: EGK_04447; G protein-activated inward rectifier potassium channel 1; GIRK1; GIRK-1; HGIRK1; inward rectifier K(+) channel Kir3.1; inward rectifier K+ channel KIR3.1; Kcnf3; Kcnj3; KGA; KGB1; KIR3.1; potassium channel inwarding rectifying channel subfamily J member 3; potassium channel subunit Kir3.1 type 3 delta; potassium channel, inwardly rectifying subfamily J member 3; potassium channel, inwardly rectifying subfamily J, member 3; potassium inwardly rectifying channel subfamily J member 3; potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e; potassium inwardly-rectifying channel, subfamily J, member 3; potassium voltage-gated channel subfamily J member 3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16519, 3760, 50599
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P48549, P63250, P63251
• Gene Symbols: KCNJ3
• Immunogen: A synthesized peptide derived from human KCNJ3(Accession P48549), corresponding to amino acid residues L161-L211.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG