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Invitrogen™ KIR3DS1 Polyclonal Antibody
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Catalog No. PIPA597295
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PIPA597295 100 μL
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Catalog No. PIPA597295 Supplier Invitrogen™ Supplier No. PA597295
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Rabbit Polyclonal Antibody

Immunogen sequence: FNMSPVTTAH AGNYTCRGSH PHSPTGWSAP SNPMVIMVTG NHRKPSLLAH PGPLVKSGER VILQCWSDIM FEHFFLHKEW ISKDPSRLVG QIHDGVSKAN FSIGSMMRAL AGTYRCYGSV THTPYQLSAP SDPLDIVVTG LYEKPSLSAQ PGPKVQAGES VTLSCSSRSS YDMYHLSREG GAHERRLPAV RKVNRTFQAD FPLGPATHGG TYRCFGSFRH SPYEWSDPSD PLLVSVTGNP SSSWPSPTEP SSKSGNLRHL H; Positive Samples: Jurkat, A-549, THP-1, BT-474, B-cell, Mouse liver, Mouse kidney, Mouse pancreas, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein.

The killer immunoglobulin-like receptors (KIRs) on natural killer (NK) cells regulate the inhibition and activation of NK-cell responses through recognition of human leukocyte antigen (HLA) class I molecules. KIR3DL1, a receptor for HLA-B antigens with the Bw4 allele, transmits an inhibitory signal to prevent killer cell-mediated cytoxicity. KIR3DL1 encodes a 444 amino acid type I transmembrane protein, containing three immunoglobulin-like C2-type domains.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIR3DS1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.97 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KIR3DS1
Gene Accession No. Q14943
Gene Alias CD158E2; killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1; killer cell immunoglobulin-like receptor 3DS1; killer cell immunoglobulin-like receptor KIR3DS1; killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1; killer Ig receptor; KIR-123FM; KIR3DS1; KIR-G1; MHC class I NK cell receptor; natural killer cell receptor; natural killer-associated transcript 10; NKAT10; NKAT-10
Gene Symbols KIR3DS1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human KIR3DS1 (NP_0010770081).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3813
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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