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Invitrogen™ Kir4.1 (KCNJ10) Polyclonal Antibody
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Catalog No. PIPA5103644
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PIPA5103644 100 μL
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Catalog No. PIPA5103644 Supplier Invitrogen™ Supplier No. PA5103644
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KCNJ10.

The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Downs syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kir4.1 (KCNJ10)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KCNJ10
Gene Accession No. P49655, P78508, Q9JM63
Gene Alias ATP-dependent inwardly rectifying potassium channel Kir4.1; ATP-sensitive inward rectifier potassium channel 10; ATP-sensitive inward rectifier potassium channel KAB-2; BIR10; BIRK1; BIRK-1; BIRK10; BIRK-10; brain-specific inwardly rectifying K(+) channel 1; glial ATP-dependent inwardly rectifying potassium channel KIR4.1; inward rectifier K(+) channel Kir1.2; Inward rectifier K(+) channel Kir4.1; inward rectifier K+ channel KIR1.2; Kab-2; Kcnj10; KCNJ13 PEN; KCNJ13-PEN; Kir1.2; Kir4.1; potassium channel, inwardly rectifying subfamily J member 10; potassium channel, inwardly rectifying subfamily J, member 10; potassium inwardly-rectifying channel, subfamily J, member 10; potassium voltage-gated channel subfamily J member 10; SESAME
Gene Symbols KCNJ10
Host Species Rabbit
Immunogen A synthesized peptide derived from human KCNJ10(Accession P78508), corresponding to amino acid residues R199-L249.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16513, 29718, 3766
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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