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Invitrogen™ Kir6.2 (KCNJ11) Polyclonal Antibody
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Catalog No. PIPA599440
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PIPA599440 100 μL
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Catalog No. PIPA599440 Supplier Invitrogen™ Supplier No. PA599440
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Kir6.2.

This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kir6.2 (KCNJ11)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Kcnj11
Gene Accession No. P70673, Q14654, Q61743
Gene Alias AI842722; ATP-sensitive inward rectifier potassium channel 11; AW491124; beta-cell inward rectifier subunit; BIR; HHF2; IKATP; Inward rectifier K(+) channel Kir6.2; inwardly rectifying potassium channel KIR6.2; IRK11; KATP; KATP channel; KCNJ11; Kir6.2; mBIR; MGC133230; MODY13; PHHI; potassium channel inwardly rectifing subfamily J member 11; potassium channel, inwardly rectifying subfamily J member 11; potassium channel, inwardly rectifying subfamily J, member 11; potassium inwardly rectifying channel, subfamily J, member 11; potassium inwardly-rectifying channel subfamily J member 11; potassium inwardly-rectifying channel, subfamily J, member 11; potassium voltage-gated channel subfamily J member 11; TNDM3
Gene Symbols Kcnj11
Host Species Rabbit
Immunogen A synthesized peptide derived from human KCNJ11(Accession Q14654), corresponding to amino acid residues L200-F250.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16514, 3767, 83535
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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