Invitrogen™ KIRREL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589723

Catalog No. PIPA589723

Description

Immunogen sequence: QGTQTRFSQE PADQTVVAGQ RAVLPCVLLN YSGIVQWTKD GLALGMGQGL KAWPRYRVVG SADAGQYNLE ITDAELSDDA SYECQATEAA LRSRRAKLTV LIPPEDTRID GGPVILLQAG TPHNLTCRAF NAKPAATIIW FRDGTQQEGA VASTELLKDG KRETTVSQLL INPTDLDIGR VFTC; Positive Samples: Mouse kidney, Mouse lung; Cellular Location: Cell membrane, Single-pass type I membrane protein.

KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003).

Specifications

• Antigen: KIRREL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Kirrel
• Gene Alias: 6720469N11Rik; FLJ10845; kin of IRRE like (Drosophila); kin of IRRE like 1; Kin of irregular chiasm-like protein 1; kin of IRRE-like protein 1; Kirrel; KIRREL1; MGC129542; MGC129543; NEPH1; nephrin 1; nephrin related; nephrin-like protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170643, 310695
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.85 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q6X936, Q80W68
• Gene Symbols: Kirrel, KIRREL1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-200 of human KIRREL (NP_0607103).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG