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Invitrogen™ KIRREL2 Polyclonal Antibody
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Catalog No. PIPA589009
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100 μL
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PIPA589009 100 μL
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Catalog No. PIPA589009 Supplier Invitrogen™ Supplier No. PA589009
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GPSPHFLQQP EDLVVLLGEE ARLPCALGAY WGLVQWTKSG LALGGQRDLP GWSRYWISGN AANGQHDLHI RPVELEDEAS YECQATQAGL RSRPAQLHVL VPPEAPQVLG GPSVSLVAGV PANLTCRSRG DARPTPELLW FRDGVLLDGA TFHQTLLKEG TPGSVESTLT LTPFSHDDGA TFVCRARSQA LPTGRDTAIT; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein.

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIRREL2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene KIRREL2
Gene Accession No. Q6UWL6, Q7TSU7
Gene Alias C330019F22Rik; DKFZp564A1164; FILTRIN; kin of IRRE like 2; kin of IRRE like 2 (Drosophila); kin of irregular chiasm-like 2; kin of irregular chiasm-like protein 2; kin of IRRE-like 2; kin of IRRE-like protein 2; kin of IRRE-like protein 2; LOW QUALITY PROTEIN: kin of IRRE-like protein 2; kirre like nephrin family adhesion molecule 2; KIRREL2; MGC15718; NEPH3; nephrin-like 3; nephrin-like gene 1; nephrin-like protein 3; NLG1; UNQ5827/PRO19646; X kin of IRRE like 2
Gene Symbols KIRREL2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human KIRREL2 (NP_9546493).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100359836, 243911, 84063
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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