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Invitrogen™ KISS1R Polyclonal Antibody

Catalog No. PIPA527180
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PIPA527180 100 μL
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Catalog No. PIPA527180 Supplier Invitrogen™ Supplier No. PA527180

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that it appears to play a role in the onset of puberty. GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KISS1R
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7
Gene KISS1R
Gene Accession No. Q969F8
Gene Alias AXOR12; CPPB1; G protein-coupled receptor 54; Gpr54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; HH8; HOT7T175; Hypogonadotropin-1; kiSS-; KiSS-1; KISS1 receptor; kiSS-1 receptor; KISS1R; KiSS-1R; Kisspeptins receptor; metastin receptor; mOT7T175; orphan G protein-coupled receptor 54; orphan G protein-coupled receptor GPR54; rOT7T175
Gene Symbols KISS1R
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Intracellular domain of human GPR54. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84634
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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