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Description
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | KIT |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | YB5.B8 |
| Conjugate | PE |
| Description | Mouse monoclonal antibody raised against KIT. |
| Dilution | Flow Cytometry The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH7.2 (0.09% Sodium azide, may contain carrier protein/stabilizer). |
| Gene Alias | C-Kit/CD117/PBT/SCFR |
| Gene Symbols | KIT |
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