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  5. 88545

Tocris Bioscience™ KL 465

Catalog No. 88545
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5 mg

Catalog No. 88-545

Supplier: Tocris Bioscience™ 8854/5

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Description

MAGE-A3 Degrader (PROTAC™)

KL 465 is a MAGE-A3 Degrader (PROTAC™) (DC50 = 2 μM; Dmax = 60%). MAGE-A3 degradation with KL 465 decreases cancer cell viability and is VHL dependent. PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

Chemical Name or Material (2S,4R)-N-(2-(2-(2-(2-((4-(Furan-2-carbonyl)piperazin-1-yl)methyl)-4-(1H-indazol-4-yl)phenoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide
CAS 3057446-82-6
Quantity 5 mg
Target Active Degraders
Molecular Formula C56H60N8O9S
Purity 0.98
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