Invitrogen™ KLB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121806

Catalog No. PIPA5121806

Description

KLB Polyclonal Antibody for Western Blot, IHC (P)

KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.

Specifications

• Antigen: KLB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLB
• Gene Alias: AV071179; Betakl; betaKlotho; beta-klotho; BKL; Klb; Klb-ps1; klotho beta; klotho beta like; klotho beta, pseudogene 1; klotho beta-like protein; MGC142213; RGD1308227
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 152831, 83379
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q86Z14, Q99N32
• Gene Symbols: KLB
• Immunogen: Recombinant protein Klotho Beta. The antigen corresponds to amino acid range 517-636 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG