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KLC1/KNS2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS11212R

Encompass_Preferred

Catalog No. 50-198-1174


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Description

Description

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.
Specifications

Specifications

KLC1/KNS2
Polyclonal
Unconjugated
KLC1
AI874768; kinesin 2; kinesin 2 60/70kDa; Kinesin light chain 1; Kinesin2; Klc; KLC 1; KLC1; KNS 2; KNS 2A; KNS2; KNS2A; medulloblastoma antigen MU-MB-2.50; MGC15245
Rabbit
Protein A
RUO
3831
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q07866
KLC1
KLH conjugated synthetic peptide derived from human KLC1.
100 μL
Primary
Human
Antibody
IgG
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