Invitrogen™ KLC1 Monoclonal Antibody (4F2D7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA549269

Catalog No. PIMA549269

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human U-87MG whole cell, rat brain tissue, rat C6 whole cell, mouse brain tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: KLC1
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4 mg trehalose and no preservative
• Gene Accession No.: O88447, P37285, Q07866
• Gene Symbols: KLC1
• Immunogen: E.coli-derived human KLC1 recombinant protein (Position: M1-D537).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 4F2D7
• Conjugate: Unconjugated
• Gene: KLC1
• Gene Alias: AI874768; kinesin 2; kinesin 2 60/70kDa; kinesin light chain 1; Kinesin2; Klc; KLC 1; Klc1; KNS 2; KNS 2A; Kns2; KNS2A; medulloblastoma antigen MU-MB-2.50; MGC15245
• Host Species: Mouse
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16593, 171041, 3831
• Content And Storage: -20°C
• Form: Lyophilized