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Invitrogen™ KLC1 Polyclonal Antibody
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Catalog No. PIPA522343
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100 μL
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PIPA522343 100 μL
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Catalog No. PIPA522343 Supplier Invitrogen™ Supplier No. PA522343
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa. Predicted reactivity: Mouse (97%), Rat (98%), Xenopus laevis (97%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLC1
Applications Western Blot
Classification Polyclonal
Concentration 0.42 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene KLC1
Gene Accession No. Q07866
Gene Alias AI874768; kinesin 2; kinesin 2 60/70kDa; kinesin light chain 1; Kinesin2; Klc; KLC 1; Klc1; KNS 2; KNS 2A; Kns2; KNS2A; medulloblastoma antigen MU-MB-2.50; MGC15245
Gene Symbols KLC1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human KLC1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3831
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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