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KLC1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501563281
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50-156-3281 100 μL
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Catalog No. 50-156-3281 Supplier Bethyl Laboratories, Inc Supplier No. A302711A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.

Specifications

Antigen KLC1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene KLC1
Gene Accession No. Q07866
Gene Alias KLC, KNS2, KNS2A, KLC 1, kinesin 2 60/70kDa, medulloblastoma antigen MU-MB-2.50
Gene Symbols KLC1
Host Species Rabbit
Immunogen Between 523 and 573
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3831
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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