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Invitrogen™ KLC1 Recombinant Rabbit Monoclonal Antibody (5C3P5)
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Catalog No. PIMA537882
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PIMA537882 100 μL
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Catalog No. PIMA537882 Supplier Invitrogen™ Supplier No. MA537882
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: 293T, MCF7, U-87MG, Mouse brain, Rat brain Immunogen sequence: GGWYKACKVD SPTVTTTLKN LGALYRRQGK FEAAETLEEA AMRSRKQGLD NVHKQRVAEV LNDPENMEKR RSRESLNVDV VKYESGPDGG EEVSMSVEWN G.

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLC1
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 5C3P5
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KLC1
Gene Accession No. O88447, P37285, Q07866
Gene Alias AI874768; kinesin 2; kinesin 2 60/70kDa; kinesin light chain 1; Kinesin2; Klc; KLC 1; Klc1; KNS 2; KNS 2A; Kns2; KNS2A; medulloblastoma antigen MU-MB-2.50; MGC15245
Gene Symbols KLC1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Kinesin light chain 1 (KLC1) (Q07866).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16593, 171041, 3831
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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