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Invitrogen™ KLDC3 Polyclonal Antibody
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Catalog No. PIPA556358
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PIPA556358 100 μL
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Catalog No. PIPA556358 Supplier Invitrogen™ Supplier No. PA556358
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FHSATMLGSH MYVFGGRADR FGPFHSNNEI YCNRIRVFDT RTEAWLDCPP TPVLPEGRRS HSAFGYNGEL YIFGGYNARL NRHFHDLWKF NPVSF Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Kelch domain-containing protein 3 (KLHDC3), also designated PEAS, contains 5 Kelch repeats and may be involved in meiotic recombination process. The gene encoding KLHDC3 maps to chromosome 6, which contains around 1, 200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. KLHDC3 protein is mainly expressed in cytoplasm, also found in meiotic chromatin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLDC3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KLHDC3
Gene Accession No. Q9BQ90
Gene Alias 1300011D16Rik; dJ20C7.3; kelch domain containing 3; kelch domain-containing protein 3; KLHDC3; Peas; Protein Peas; RP1-20C7.3; testis intracellular mediator protein
Gene Symbols KLHDC3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KLDC3. Recombinant protein control fragment (Product #RP-94799).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116138
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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