Invitrogen™ KLF17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531774

Catalog No. PIPA531774

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Human (98%), Chimpanzee (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

Specifications

• Antigen: KLF17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLF17
• Gene Alias: 7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; FLJ40160; germ cell specific zinc finger protein; germ cell-specific zinc finger protein; Gzf; KLF17; Krueppel-like factor 17; Kruppel like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zfp393; Zinc finger protein 393; ZLF393; ZNF393
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 128209
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q5JT82
• Gene Symbols: KLF17
• Immunogen: Recombinant protein encompassing a sequence within the center region of human KLF17. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG