Invitrogen™ KLF17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589403

Catalog No. PIPA589403

Description

Immunogen sequence: QMLPPQDAHD LGMPPAESQS LLVLGSQDSL VSQPDSQEGP FLPEQPGPAP QTVEKNSRPQ EGTGRRGSSE ARPYCCNYEN CGKAYTKRSH LVSHQRKHTG ERPYSCNWES CSWSFFRSDE LRRHMRVHTR YRPYKCDQCS REFMRSDHLK QHQKTHRPGP SDPQANNNNG EQDSPPAAGP; Positive Samples: U-87MG, HepG2, MCF7, Mouse brain; Cellular Location: Nucleus.

KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

Specifications

• Antigen: KLF17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLF17
• Gene Alias: 7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; FLJ40160; germ cell specific zinc finger protein; germ cell-specific zinc finger protein; Gzf; KLF17; Krueppel-like factor 17; Kruppel like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zfp393; Zinc finger protein 393; ZLF393; ZNF393
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 128209, 75753
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q5JT82, Q8CFA7
• Gene Symbols: KLF17
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_7757553).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov