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KLF2/4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980953
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100 μL
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50-198-0953 100 μL
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Catalog No. 50-198-0953 Supplier Bioss Supplier No. BS1064R
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Rabbit Polyclonal Antibody

Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a family of conserved Kruppel-like factor family of DNA binding zinc finger transcription factors. KLF4 exerts its functional relevance across varied cellular pathways. As one of the four Yamanaka factors, it plays a key role in reprogramming differentiated cells into pluripotent stem cells. Most studies have focused on its specific role in endothelial cell signaling, adipogenesis, differentiation, embryogenesis and cell cycle control. Localization plays an important role in the biological significance of this protein wherein nuclear localization is associated with its function as an oncogene and cytosolic localization with tumor suppression specific effect.

Specifications

Antigen KLF2/4
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene KLF4
Gene Accession No. O43474
Gene Alias BOS_9305; endothelial Kruppel-like zinc finger protein; Epithelial zinc finger protein EZF; EZF; Gklf; gut Kruppel-like factor; Gut-enriched krueppel-like factor; Klf4; Krueppel-like factor 4; Kruppel like factor 4; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); RP11-150J11.1; Zie
Gene Symbols KLF4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human KLF4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9314
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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