Invitrogen™ KLF3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530621

Catalog No. PIPA530621

Description

Recommended positive controls: A549, HCT116. Predicted reactivity: Human (99%), Mouse (98%), Rat (99%), Pig (99%), Rhesus Monkey (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Krueppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the coregulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Kruppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis.

Specifications

• Antigen: KLF3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klf3
• Gene Alias: 9930027G08Rik; AL024007; Basic krueppel-like factor; basic kruppel like factor; Basic Kruppel- like factor; basic Kruppel-like factor; BKLF; CACCC-box-binding protein BKLF; klf12; Klf3; Krueppel-like factor 3; kruppel like factor 12; Kruppel like factor 3; Kruppel-like factor 12; Kruppel-like factor 3 (basic); MGC48279; TEF-2; transcript ch138; zinc finger containing transcription factor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51274
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P57682
• Gene Symbols: Klf3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human KLF3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG