Invitrogen™ KLF3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566743

Catalog No. PIPA566743

Description

Immunogen sequence: LMFDPVPVKQE AMDPVSVSYP SNYMESMKPN KYGVIYSTPL PEKFFQTPEG LSHGIQMEPV DL Highest antigen sequence identity to the following orthologs - mouse 92%, rat 94%.

Krueppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the coregulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Kruppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis.

Specifications

• Antigen: KLF3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klf3
• Gene Alias: 9930027G08Rik; AL024007; Basic krueppel-like factor; basic kruppel like factor; Basic Kruppel- like factor; basic Kruppel-like factor; BKLF; CACCC-box-binding protein BKLF; klf12; Klf3; Krueppel-like factor 3; kruppel like factor 12; Kruppel like factor 3; Kruppel-like factor 12; Kruppel-like factor 3 (basic); MGC48279; TEF-2; transcript ch138; zinc finger containing transcription factor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51274
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P57682
• Gene Symbols: Klf3
• Immunogen: Recombinant Human KLF3. Recombinant protein control fragment (Product #RP-107399).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov