Invitrogen™ KLHL12 Monoclonal Antibody (2G11D1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA549300

Catalog No. PIMA549300

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human PC-3 whole cell, human 293T whole cell, human Hela whole cell, human Jurkat whole cell, rat brain tissue, rat PC-12 whole cell, mouse brain tissue, mouse RAW2647 whole cell. IHC: human liver cancer tissue, human thyroid cancer tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

Specifications

• Antigen: KLHL12
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: Q53G59, Q8BZM0, Q8R2H4
• Gene Symbols: Klhl12
• Immunogen: E.coli-derived human KLHL12 recombinant protein (Position: R27-I331).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 2G11D1
• Conjugate: Unconjugated
• Gene: Klhl12
• Gene Alias: C3IP1; CUL3-interacting protein 1; DKIR; DKIR homolog; FLJ27152; hDKIR; kelch like family member 12; kelch-like 12; kelch-like family member 12; kelch-like protein 12; kelch-like protein C3IP1; Klhl12; si:dkeyp-53e12.5; Unknown (protein for MGC:134560); wu:fi60g03; zgc:92570
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 240756, 266772, 59349
• Content And Storage: -20°C
• Form: Lyophilized