Invitrogen™ KLHL12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531278

Catalog No. PIPA531278

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (87%), Xenopus laevis (90%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

Specifications

• Antigen: KLHL12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klhl12
• Gene Alias: C3IP1; CUL3-interacting protein 1; DKIR; DKIR homolog; FLJ27152; hDKIR; kelch like family member 12; kelch-like 12; kelch-like family member 12; kelch-like protein 12; kelch-like protein C3IP1; Klhl12; si:dkeyp-53e12.5; Unknown (protein for MGC:134560); wu:fi60g03; zgc:92570
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 59349
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q53G59
• Gene Symbols: Klhl12
• Immunogen: Recombinant fragment corresponding to a region within amino acids 81 and 341 of Human C3IP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG