Invitrogen™ KLHL22 Monoclonal Antibody (7B10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515699

Catalog No. PIMA515699

Description

MA5-15699 targets KLHL22 in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15699 immunogen is purified recombinant fragment of human KLHL22 expressed in E. Coli. MA5-15699 detects KLHL22 which has a predicted molecular weight of approximately 72kDa.

KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.

Specifications

• Antigen: KLHL22
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q53GT1, Q99JN2
• Gene Symbols: KLHL22
• Immunogen: Purified recombinant fragment of human KLHL22 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 224023, 84861
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 7B10
• Conjugate: Unconjugated
• Gene: KLHL22
• Gene Alias: 2610318I18Rik; kelch like family member 22; KELCHL; kelch-like 22; kelch-like family member 22; kelch-like protein 22; KLHL22; RGD1306288
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1