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Invitrogen™ KLHL22 Monoclonal Antibody (7B10)
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Catalog No. PIMA515699
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100 μL
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Catalog No. Quantity
PIMA515699 100 μL
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Catalog No. PIMA515699 Supplier Invitrogen™ Supplier No. MA515699
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Description

Mouse Monoclonal Antibody

MA5-15699 targets KLHL22 in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15699 immunogen is purified recombinant fragment of human KLHL22 expressed in E. Coli. MA5-15699 detects KLHL22 which has a predicted molecular weight of approximately 72kDa.

KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLHL22
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7B10
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene KLHL22
Gene Accession No. Q53GT1, Q99JN2
Gene Alias 2610318I18Rik; kelch like family member 22; KELCHL; kelch-like 22; kelch-like family member 22; kelch-like protein 22; KLHL22; RGD1306288
Gene Symbols KLHL22
Host Species Mouse
Immunogen Purified recombinant fragment of human KLHL22 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 224023, 84861
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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