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Invitrogen™ KLHL22 Polyclonal Antibody
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Catalog No. PIPA532054
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100 μL
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Catalog No. Quantity
PIPA532054 100 μL
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Catalog No. PIPA532054 Supplier Invitrogen™ Supplier No. PA532054
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, HeLa, HepG2. Predicted reactivity: Mouse (93%), Rat (93%), Rhesus Monkey (100%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLHL22
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.04 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene KLHL22
Gene Accession No. Q53GT1
Gene Alias 2610318I18Rik; kelch like family member 22; KELCHL; kelch-like 22; kelch-like family member 22; kelch-like protein 22; KLHL22; RGD1306288
Gene Symbols KLHL22
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human KLHL22. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84861
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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