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KLK3 Mouse anti-Human, Clone: 2B7, Abnova™

Catalog No. 89934410 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-934-410 50 μg
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Catalog No. 89-934-410 Supplier Abnova Corporation Supplier No. MAB12990

Description

Mouse monoclonal antibody raised against human KLK3.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq]

Specifications

Antigen KLK3
Applications ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone 2B7
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against human KLK3.
Dilution ELISA Flow Cytometry Immunocytochemistry Immunohistochemistry (Frozen sections) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot The optimal working dilution should be determined by the end use
Formulation In PBS (0.09% sodium azide).
Gene Alias APS/KLK2A1/PSA/hK3
Gene Symbols KLK3
Host Species Mouse
Immunogen Human Prostate-specific antigen (PSA).
Purification Method Protein G purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 354
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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