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Klotho Monoclonal Antibody (C3), Invitrogen™

Mouse Monoclonal Antibody

$243.00 - $522.50

Specifications

Antigen Klotho
Clone C3
Concentration 1 mg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIMA543727
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Invitrogen™
MA543727
20 μL
Each for $243.00
Only null left
Add to Cart
 
PIMA543726
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Invitrogen™
MA543726
100 μL
Each for $522.50
Only null left
Add to Cart
 
Description

Description

KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
Specifications

Specifications

Klotho
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
KL
IgG1 κ
Protein A/G
Antibody
C3
Western Blot
Unconjugated
Mouse
Human
Q9UEF7
9365
Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag.
Primary
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
KL
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SDS
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Documents

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