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Invitrogen™ KLRC2/KLRC4 Polyclonal Antibody
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Catalog No. PIPA599852
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PIPA599852 100 μL
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Catalog No. PIPA599852 Supplier Invitrogen™ Supplier No. PA599852
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KLRC2/4.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLRC2/KLRC4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KLRC2
Gene Accession No. O43908, P26717
Gene Alias CD159 antigen-like family member C; CD159c; killer cell lectin like receptor C2; killer cell lectin like receptor C4; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 4; KLRC2; KLRC4; natual killer cell group 2-F; NK cell receptor C; NK cell receptor F; NKG2C; NKG2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; Nkg2E; NKG2F; NKG2-F; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor; rNKG2C
Gene Symbols KLRC2, KLRC4
Host Species Rabbit
Immunogen A synthesized peptide derived from human KLRC2(Accession P26717), corresponding to amino acid residues M1-Q40.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16642, 29684, 3822, 8302
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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