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Invitrogen™ KLRC4 Polyclonal Antibody
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Catalog No. PIPA521950
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100 μL
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PIPA521950 100 μL
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Catalog No. PIPA521950 Supplier Invitrogen™ Supplier No. PA521950
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T. Predicted reactivity: Chimpanzee (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The KLRC4 (Killer Cell Lectin Like Receptor C4) gene encodes a member of the NKG2 family of receptors, which are expressed mostly on natural killer (NK) cells and some T lymphocytes. This gene is located on chromosome 12 and plays a key role in immune surveillance and the activation of NK cells. The KLRC4 protein, also known as NKG2F, interacts with other receptors such as KLRK1 (NKG2D) to recognize stress-induced ligands on potential target cells, thereby mediating their destruction. Variants and polymorphisms in KLRC4 have been investigated in various immune-related conditions, including their association with thyroid diseases and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLRC4
Applications Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene KLRC4
Gene Accession No. O43908
Gene Alias killer cell lectin like receptor C4; killer cell lectin-like receptor subfamily C, member 4; KLRC4; natual killer cell group 2-F; NK cell receptor F; NKG2F; NKG2-F; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor
Gene Symbols KLRC4
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Intracellular domain of human KLRC4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8302
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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