Invitrogen™ KMT2C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144903

Catalog No. FEPA5144903

Description

Immunogen sequence: DTQLKEEYIC MYCKHLGAEM DRLQPGEEVE IAELTTDYNN EMEVEGPEDQ MVFSEQAANK DVNGQESTPG IVPDAVQVHT EEQQKSHPSE SL Antigen sequence identity: Mouse 67%; Rat 67%.

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Specifications

• Antigen: KMT2C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KMT2C
• Gene Alias: 2.1.1.43; ALR-like protein; HALR; Histone-lysine N-methyltransferase 2C; histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase, H3 lysine-4 specific; homologous to ALR protein; KIAA1506; KMT2C; lysine (K)-specific methyltransferase 2C; lysine methyltransferase 2C; Lysine N-methyltransferase 2C; MLL3; Myeloid/lymphoid or mixed-lineage leukemia protein 3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58508
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NEZ4
• Gene Symbols: KMT2C
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 505-596. Recombinant protein control fragment (Product #RP-109822).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid