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Invitrogen™ KMT2D Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549581

Catalog No. PA549581


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Description

Description

KMT2D Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chormatin silencig, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congential mental retardation syndrome.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

KMT2D
Polyclonal
Unconjugated
KMT2D
AAD10; ALL1-related protein; ALR; CAGL114; Histone-lysine N-methyltransferase 2D; histone-lysine N-methyltransferase MLL2; KABUK1; Kabuki make-up syndrome; Kabuki mental retardation syndrome; KMS; KMT2D; lysine (K)-specific methyltransferase 2D; lysine methyltransferase 2D; lysine N-methyltransferase 2D; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia 2; Myeloid/lymphoid or mixed-lineage leukemia protein 2; TNRC21; trinucleotide repeat containing 21
Rabbit
Antigen Affinity Chromatography, Protein A
RUO
8085
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.4
O14686
KMT2D
KLH conjugated synthetic peptide between 4980-5009 amino acids from the C-terminal region of human MLL2.
400 μL
Primary
Human
Antibody
IgG
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