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KMT2D Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 272661AP150UL

Encompass_Preferred

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Catalog No. 50-173-5625


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Description

Description

KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chromatin silencing, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congenital mental retardation syndrome.
Specifications

Specifications

KMT2D
Polyclonal
Unconjugated
KMT2D
AAD10, ALL1 related protein, ALR, CAGL114, KMT2B, KMT2D, Lysine N methyltransferase 2B, MLL2, MLL4, TNRC21
Rabbit
Antigen Affinity Chromatography
RUO
8085
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.43 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O14686
KMT2D
KMT2D Fusion Protein Ag26195
150 μL
Primary
Human
Antibody
IgG
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