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KMT2D Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735625 Shop All Proteintech Group Inc Products
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50-173-5625 150 μL
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Catalog No. 50-173-5625 Supplier Proteintech Group Inc Supplier No. 272661AP150UL
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Description

Rabbit Polyclonal Antibody

KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chromatin silencing, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congenital mental retardation syndrome.

Specifications

Antigen KMT2D
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene KMT2D
Gene Accession No. O14686
Gene Alias AAD10, ALL1 related protein, ALR, CAGL114, KMT2B, KMT2D, Lysine N methyltransferase 2B, MLL2, MLL4, TNRC21
Gene Symbols KMT2D
Host Species Rabbit
Immunogen KMT2D Fusion Protein Ag26195
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8085
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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