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kNBC Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2096R

Encompass_Preferred

Catalog No. 50-198-4514


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Description

Description

Slc4a4 encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Slc4a4 is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. Moreover, Slc4a4 may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. Isoform 2: May have a higher activity than isoform 1. Mutations in the Slc4a4 gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for the Slc4a4 gene. Diseases associated with SLC4A4 include Renal Tubular Acidosis, Proximal, With Ocular Abnormalities and Proximal Renal Tubular Acidosis.
Specifications

Specifications

kNBC
Polyclonal
Unconjugated
SLC4A4
AI835705; Electrogenic sodium bicarbonate cotransporter 1; electrogenic sodium bicarbonate cotransporter NBCe1 variant D; HHNMC; HNBC 1; HNBC1; KNBC; kNBC 1; kNBC1; Na(+)/HCO3(-) cotransporter; Na+HCO3- cotransporter 4; Nbc; NBC 1; NBC 2; NBC1; NBC2; Nbc4; NBCE 1; NBCE1; NBCe1-A; NBC-like protein; OTTHUMP00000160355; OTTHUMP00000218884; OTTHUMP00000218885; pancreas sodium bicarbonate cotransporter; pNBC; Rnbc1; SLC4A4; SLC4A5; Sodium bicarbonate cotransporter; sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney; sodium bicarbonate cotransporter, pancreas); solute carrier family 4 (anion exchanger), member 4; solute carrier family 4 (sodium bicarbonate cotransporter), member 4; Solute carrier family 4 member 4; solute carrier family 4, member 4; solute carrier family 4, sodium bicarbonate cotransporter, member 4; solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type; solute carrier family 4, sodium bicarbonate cotransporter, member 5
Rabbit
Protein A
RUO
8671
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q9Y6R1
SLC4A4
KLH conjugated synthetic peptide derived from Mouse electrogenic sodium bicarbonate cotransporter isoform 2.
100 μL
Primary
Human
Antibody
IgG
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