Invitrogen™ KNT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5122191

Catalog No. PIPA5122191

Description

KNT1 Polyclonal Antibody for Western Blot, IHC (P)

KNT1 (T-Kinninogen 1) is the acute phase kininogen of the rat. KNT1 could be a healing protein because of its properties as a cysteine protease inhibitor. Evidence has been presented that mRNA of T-kininogen synthesis may be a function of interleukin 6 production. In rats, four types of kininogens are produced, two of which are classical high and low molecular weight kininogens and two of which are low molecular weight-like kininogens, designated T-kininogen 1 and T-kininogen 2. T-kininogen 1 and T-kininogen 2 are 430 amino acid secreted rat proteins that each contain three cystatin domains and have nearly identical functions. Existing in plasma, both T-kininogen 1 and T-kininogen 2 are glycoproteins that act as thiol protease inhibitors and also play a role in blood coagulation, specifically by helping to optimally position blood coagulation factors.

Specifications

• Antigen: KNT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Kng1
• Gene Alias: T-Kinninogen 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 288001
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P08934
• Gene Symbols: Kng1
• Immunogen: Recombinant protein T-Kininogen 1. The antigen corresponds to amino acid range 378-430 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG