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Invitrogen™ KPNA1 Polyclonal Antibody
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Catalog No. PIPA529474
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100 μL
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PIPA529474 100 μL
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Catalog No. PIPA529474 Supplier Invitrogen™ Supplier No. PA529474
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Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (96%), Rat (97%), Pig (98%), Chicken (94%), Rhesus Monkey (99%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Recombination activating proteins RAG1 and RAG2 regulate and mediate VJ recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in VJ recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KPNA1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.64 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene KPNA1
Gene Accession No. P52294, Q60960
Gene Alias AW494490; IMA2; Importin alpha 2; importin alpha 5; Importin alpha P1; importin alpha-5; importin alpha-S1; importin subunit alpha-1; importin subunit alpha-5; Importin subunit alpha-5, N-terminally processed; importin-alpha-S1; IPOA 1; IPOA1; IPOA5; karyopherin (importin) alpha 1; Karyopherin A2; karyopherin alpha 1; karyopherin alpha 1 (importin alpha 5); karyopherin subunit alpha 1; karyopherin subunit alpha-1; karyopherin/importin alpha-1; KPNA1; KPNA2; m-importin-alpha-S1; mSRP1; NPI1; NPI-1; Nucleoprotein interactor 1; RAG cohort 1; RAG cohort protein 2; RCH 1; RCH1; RCH2; recombination activating gene cohort 2; SRP 1; SRP1; SRP1 alpha; SRP1-beta
Gene Symbols KPNA1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SRP1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16646, 3836
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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