Invitrogen™ KPNA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102471

Catalog No. PIPA5102471

Description

Antibody detects endogenous levels of total KPNA1.

Recombination activating proteins RAG1 and RAG2 regulate and mediate VJ recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in VJ recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.

Specifications

• Antigen: KPNA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KPNA1
• Gene Alias: AW494490; IMA2; Importin alpha 2; importin alpha 5; Importin alpha P1; importin alpha-5; importin alpha-S1; importin subunit alpha-1; importin subunit alpha-5; Importin subunit alpha-5, N-terminally processed; importin-alpha-S1; IPOA 1; IPOA1; IPOA5; karyopherin (importin) alpha 1; Karyopherin A2; karyopherin alpha 1; karyopherin alpha 1 (importin alpha 5); karyopherin subunit alpha 1; karyopherin subunit alpha-1; karyopherin/importin alpha-1; KPNA1; KPNA2; m-importin-alpha-S1; mSRP1; NPI1; NPI-1; Nucleoprotein interactor 1; RAG cohort 1; RAG cohort protein 2; RCH 1; RCH1; RCH2; recombination activating gene cohort 2; SRP 1; SRP1; SRP1 alpha; SRP1-beta
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16646, 288064, 3836
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P52294, P83953, Q60960
• Gene Symbols: KPNA1
• Immunogen: A synthesized peptide derived from human KPNA1(Accession P52294), corresponding to amino acid residues M1-L33.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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