Invitrogen™ KPNA4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521749

Catalog No. PIPA521749

Description

Recommended positive controls: 293T, HeLa, HepG2, Molt-4, Raji, A549. Predicted reactivity: Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Specifications

• Antigen: KPNA4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KPNA4
• Gene Alias: 1110058D08Rik; importin; Importin alpha Q1; importin subunit alpha-3; importin subunit alpha-4; importin-alpha-Q1; IPOA3; karyopherin (importin) alpha 4; karyopherin alpha 4; karyopherin alpha 4 (importin alpha 3); karyopherin subunit alpha 4; karyopherin subunit alpha-4; KPNA4; MGC12217; MGC26703; predicted role in nuclear import; qip1; Qip1 protein; SRP3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16649, 361959, 3840
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.04 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O00629, O35343
• Gene Symbols: KPNA4
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KPNA4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov