Invitrogen™ KPNA4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596038

Catalog No. PIPA596038

Description

Immunogen sequence: MADNEKLDNQ RLKNFKNKGR DLETMRRQRN EVVVELRKNK RDEHLLKRRN VPHEDICEDS DIDGDYRVQN TSLEAIVQNA SSDNQGIQLS AVQAARKLLS SDRNPPIDDL IKSGILPILV HCLERDDNPS LQFEAAWALT NIASGTSEQT QAVVQSNAVP LFLRLLHSPH QNVCEQAVWA LGNIIGDGPQ CRDYVISLGV VKPLLSFISP SIPITFLRNV TWVMVNLCRH KDPPPPMETI; Positive Samples: BT-474, A-549, SKOV3, Mouse spleen; Cellular Location: Cytoplasm, Nucleus.

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Specifications

• Antigen: KPNA4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KPNA4
• Gene Alias: 1110058D08Rik; importin; Importin alpha Q1; importin subunit alpha-3; importin subunit alpha-4; importin-alpha-Q1; IPOA3; karyopherin (importin) alpha 4; karyopherin alpha 4; karyopherin alpha 4 (importin alpha 3); karyopherin subunit alpha 4; karyopherin subunit alpha-4; KPNA4; MGC12217; MGC26703; predicted role in nuclear import; qip1; Qip1 protein; SRP3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16649, 361959, 3840
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.12 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O00629, O35343
• Gene Symbols: KPNA4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human KPNA4 (NP_0022591).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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