Invitrogen™ KPNA7 Polyclonal Antibody

Catalog No.	Quantity
PIPA570789	100 μL

Catalog No. PIPA570789 Supplier Invitrogen™ Supplier No. PA570789

Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 79%; Dog: 93%; Human: 100%; Pig: 79%; Yeast: 90%.

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.

Specifications

• Antigen: KPNA7
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene: KPNA7
• Gene Accession No.: A9QM74
• Gene Alias: importin alpha 8; importin subunit alpha-8; IPOA8; karyopherin 7; karyopherin alpha 7 (importin alpha 8); karyopherin subunit alpha 7; Karyopherin subunit alpha-7; KPNA7
• Gene Symbols: KPNA7
• Host Species: Rabbit
• Immunogen: synthetic peptide directed towards the C-terminal region of human KPNA7.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 402569
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG