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Invitrogen™ KPNA7 Polyclonal Antibody
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Catalog No. PIPA534372
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100 μg
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Catalog No. Quantity
PIPA534372 100 μg
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Catalog No. PIPA534372 Supplier Invitrogen™ Supplier No. PA534372
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Description

Rabbit Polyclonal Antibody

PA5-34372 can be used with blocking peptide PEP-1415.

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KPNA7
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene KPNA7
Gene Accession No. A9QM74
Gene Alias importin alpha 8; importin subunit alpha-8; IPOA8; karyopherin 7; karyopherin alpha 7 (importin alpha 8); karyopherin subunit alpha 7; Karyopherin subunit alpha-7; KPNA7
Gene Symbols KPNA7
Host Species Rabbit
Immunogen A 13 amino acid synthetic peptide near the amino terminus of human KPNA7.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 402569
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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