Invitrogen™ KPNA7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534372

Catalog No. PIPA534372

Description

PA5-34372 can be used with blocking peptide PEP-1415.

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.

Specifications

• Antigen: KPNA7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KPNA7
• Gene Alias: importin alpha 8; importin subunit alpha-8; IPOA8; karyopherin 7; karyopherin alpha 7 (importin alpha 8); karyopherin subunit alpha 7; Karyopherin subunit alpha-7; KPNA7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 402569
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: A9QM74
• Gene Symbols: KPNA7
• Immunogen: A 13 amino acid synthetic peptide near the amino terminus of human KPNA7.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG