KRT14 Monoclonal Antibody (OTI4A7), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-9655	100 μL

Catalog No. 50-167-9655 Supplier OriGene Supplier No. TA803267

Description

Mouse Monoclonal Antibody

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.

Specifications

• Antigen: KRT14
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI4A7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: KRT14
• Gene Accession No.: P02533
• Gene Alias: CK14, EBS3, EBS4, K14, NFJ
• Gene Symbols: KRT14
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 261-472 of human KRT14 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3861
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a