KRT14 Mouse anti-Human, Clone: OTI3C7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF801254

Catalog No. 50-166-5519

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.

Specifications

• Antigen: KRT14
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: KRT14
• Gene Alias: CK14, EBS3, EBS4, K14, NFJ
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3861
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3C7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P02533
• Gene Symbols: KRT14
• Immunogen: Human recombit protein fragment corresponding to amino acids 148-472 of human KRT14 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b