KRT5/KRT8 Mouse anti-Human, Clone: SPM268, Abnova™
Mouse monoclonal antibody raised against native human KRT5/KRT8.
Manufacturer: Abnova Corporation MAB13198
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq]
|Mouse monoclonal antibody raised against native human KRT5/KRT8.|
|In 10mM PBS, pH 7.4.|
|Store at 4°C.|
|Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be dete|
|Cytoskeletal preparation from HeLa cells.|
|Protein A/G purification|
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