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Invitrogen™ KRT81 Polyclonal Antibody
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Catalog No. PIPA5100852
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PIPA5100852 100 μL
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Catalog No. PIPA5100852 Supplier Invitrogen™ Supplier No. PA5100852
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KRT81.

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KRT81
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KRT81
Gene Accession No. Q14533
Gene Alias AA589625; ghHb1; ghHkb1; Hair keratin K2.9; hard keratin, type II, 1; HB1; Hb-1; hHAKB2-1; K81; Kb21; keratin 81; keratin 81, type II; keratin complex 2, basic, gene 19; keratin, hair, basic, 1; Keratin, type II cuticular Hb1; keratin-81; Krt2-19; KRT81; KRTHB1; Metastatic lymph node 137 gene protein; MLN 137; MLN137; type II hair keratin Hb1; type II keratin Kb21; type-II keratin Kb21
Gene Symbols KRT81
Host Species Rabbit
Immunogen A synthesized peptide derived from human KRT81(Accession Q14533), corresponding to amino acid residues P470-C505.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3887
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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