Invitrogen™ KRT81 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550197

Catalog No. PA550197

Description

The antibody detects endogenous levels of total KRT81 protein.

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

Specifications

• Antigen: KRT81
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KRT81
• Gene Alias: AA589625; ghHb1; ghHkb1; Hair keratin K2.9; hard keratin, type II, 1; HB1; Hb-1; hHAKB2-1; K81; Kb21; keratin 81; keratin 81, type II; keratin complex 2, basic, gene 19; keratin, hair, basic, 1; Keratin, type II cuticular Hb1; keratin-81; Krt2-19; KRT81; KRTHB1; Metastatic lymph node 137 gene protein; MLN 137; MLN137; type II hair keratin Hb1; type II keratin Kb21; type-II keratin Kb21
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3887
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q14533
• Gene Symbols: KRT81
• Immunogen: Fusion protein corresponding to residues near the N terminal of human keratin 81.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG