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KRT81 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550197

Catalog No. PA550197


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Description

Description

The antibody detects endogenous levels of total KRT81 protein.

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare domit hair disease, monilethrix.
Specifications

Specifications

KRT81
Polyclonal
Unconjugated
KRT81
Liquid
KRT81
Fusion protein corresponding to residues near the N terminal of human keratin 81
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.8 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q14533
KRTHB1, MLN137
Rabbit
IgG
100 μL
-20°C
Primary
3887
Documents
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