KRT84 Mouse anti-Human, Clone: OTI2D1, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0505	100 μg

Catalog No. 50-167-0505 Supplier OriGene Supplier No. CF811189

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The Keratin multigene family is made of "soft" epithelial cytokeratins and "hard" hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.

Specifications

• Antigen: KRT84
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: OTI2D1
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: KRT84
• Gene Accession No.: Q9NSB2
• Gene Alias: HB4, KRTHB4
• Gene Symbols: KRT84
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human KRT84 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3890
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1