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Invitrogen™ KRT84 Polyclonal Antibody
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Catalog No. PIPA565244
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100 μL
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PIPA565244 100 μL
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Catalog No. PIPA565244 Supplier Invitrogen™ Supplier No. PA565244
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CGVRFGAGCGM GFGDGRGVGL GPRADSCVGL GFGAGSGIGY GFGGPGFGYR VGGVGVPAAP SITAV Highest antigen sequence identity to the following orthologs - mouse 61%, rat 62%.

The Keratin multigene family is made of soft epithelial cytokeratins and hard hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KRT84
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KRT84
Gene Accession No. Q9NSB2
Gene Alias 65 kDa type II keratin; AV235125; hard keratin, type II, 4; HB4; HRb-1; K84; Kb24; keratin 84; keratin 84, type II; keratin complex 2, basic, gene 16; keratin complex 2, gene 16; keratin, hair, basic, 4; keratin, type II cuticular Hb4; Keratin-84; Krt2-16; Krt2-3; Krt84; KRTHB4; type II hair keratin 4; type II hair keratin Hb4; type II keratin Kb24; type-II keratin Kb24
Gene Symbols KRT84
Host Species Rabbit
Immunogen Recombinant Human KRT84. Recombinant protein control fragment (Product #RP-105966).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3890
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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